Jianli Lu¹ , Fan Wang²

1 Traditional Chinese Medicine Research Center, Cuixi Academy of Biotechnology, Zhuji, 311800, Zhejiang, China
2 Aquatic Biology Research Center, Cuixi Academy of Biotechnology, Zhuji, 311800, Zhejiang, China
Author    Correspondence author
Medicinal Plant Research, 2024, Vol. 14, No. 3   doi: 10.5376/mpr.2024.14.0014
Received: 29 Apr., 2024    Accepted: 02 Jun., 2024    Published: 21 Jun., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Lu J.L., and Wang F., 2024, Phytochemical properties and therapeutic potential of Hydrocotyle vulgaris: a systematic review, Medicinal Plant Research, 14(3): 162-170 (doi: 10.5376/mpr.2024.14.0014)

Hydrocotyle vulgaris has been widely used in various folk remedies, and its rich phytochemical constituents, such as flavonoids, alkaloids, and tannins, have attracted the attention of modern scientific research. This study provides a comprehensive analysis of the phytochemical composition of Hydrocotyle vulgaris and its antioxidant, anti-inflammatory, antimicrobial, antiviral, neuroprotective, and cardiovascular health benefits through a systematic review of the existing literature. Various analytical methods, such as UV-visible spectroscopy and high-performance liquid chromatography (HPLC), were evaluated, along with the quantitative analysis of its vitamin content. Additionally, this study delves into how Hydrocotyle vulgaris influences cellular metabolism by modulating signaling pathways and gene expression, as well as its role in regulating oxidative stress, immune system function, and inflammatory pathways. Although current research has highlighted its therapeutic potential, more data on its long-term safety and toxicity are required. This study provides a theoretical foundation for the further development and application of Hydrocotyle vulgaris, while also exploring its potential in modern drug development through the integration of herbal medicine.

Hydrocotyle vulgaris; Phytochemical composition; Antioxidant properties; Signal pathway modulation; Safety