Wei Dong , Yongliang Yu , Lanjie Xu , Hongqi Yang , Qing Yang , Huizhen Liang

Institute of Chinese Herbal Medicine, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, China
Author    Correspondence author
Medicinal Plant Research, 2024, Vol. 14, No. 1   doi: 10.5376/mpr.2024.14.0005
Received: 10 Jan., 2024    Accepted: 16 Feb., 2024    Published: 28 Feb., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Dong W., Yu Y.L., Xu L.J., Yang H.Q., Yang Q., and Liang H.Z., 2024, Clinical applications and efficacy of Achyranthes bidentata in bone and joint disorders, Medicinal Plant Research, 14(1): 57-70 (doi: 10.5376/mpr.2024.14.0005)

Achyranthes bidentata Bl., a traditional Chinese medicine, is widely used for its therapeutic effects on bone and joint disorders. This study introduces the botanical characteristics and pharmacologically active components of Achyranthes bidentata, and it thoroughly explores the pharmacological actions of these components, such as anti-inflammatory, antioxidant, immunomodulatory, and bone and cartilage protective functions. The study analyzes the application of Achyranthes bidentata in clinical trials, particularly its efficacy and safety in the treatment of diseases such as osteoarthritis, rheumatoid arthritis, and osteoporosis. By comparing the effectiveness of Achyranthes bidentata with conventional treatments and its synergistic effects in multi-drug formulations, the potential of Achyranthes bidentata as an alternative or complementary therapy is evaluated. Finally, the study points out the current research deficiencies and future research directions. This study aims to deeply evaluate the clinical applications and efficacy of Achyranthes bidentata in the treatment of bone and joint disorders, to promote further application and research of this herb.

Achyranthes bidentata; Bone and joint disorders; Pharmacological properties; Clinical trials; Efficacy evaluation