Review and Progress

Chinese Patent Traditional Medication Containing Aristolochic Acid and its Herbal Medicinal Plant, Efficacy and Harmfulness  

Xuanjun Fang 1,2
1 Institute of Life Science, Jiyang College of Zhejiang A&F University, Zhuji, 311800
2 Cuixi Academy of Biotechnology, Zhuji, 311800
Author    Correspondence author
Medicinal Plant Research, 2020, Vol. 10, No. 2   doi: 10.5376/mpr.2020.10.0002
Received: 06 Apr., 2020    Accepted: 26 Apr., 2020    Published: 27 Apr., 2020
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This article was first published in Zhongyi Zhongyao Yanjiu (TCM Research) in Chinese, and here was authorized to translate and publish the paper in English under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Fang, 2020, Chinese patent traditional medication containing aristolochic acid and its herbal medicinal plant, efficacy and harmfulness, Medicinal Plant Research, 10(2): 1-12 (doi: 10.5376/mpr.2020.10.0002)


The nephrotoxicity of traditional herbal medications containing aristolochial acid has attracted wide attention in China and abroad, and some countries have banned the use of traditional herbal medications containing aristolochic acid. In this study, the traditional herbal materials and patent traditional herbal medications containing aristolochic acid were statistically analyzed. Among the common traditional herbal medications containing aristolochic acid, there are 14 kinds of aristolochic plants and 10 kinds of Asarum plants,of which there are 24 kinds of herbal materials from the family of Aristolochiaceae that may contain aristolochic acid and 47 kinds of patent traditional herbal medications that have been listed that may contain aristolochic acid from the genus of Aristolochia L.. In this review, these medicinal plants were systematically analyzed. It was concluded that the renal toxicity of herbal medication containing aristolochic acid should be paid enough attentions even though Aristolochia herbs have a special significance in traditional herbal medication of China.

Chinese patent traditional medication; Traditional herbal plant; Aristolochic acid; Aristolochia L.; Asarum L.
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