Research Report
Industrial-Scale Cultivation of Ganoderma lucidum: Challenges and Technological Innovations 
2 Longquan Xianzhitang Biological Technology Co., Ltd., Longquan, 323700, Zhejiang, China
3 Zhejiang Yuanjian Biopharmaceutical Co., Ltd., Longquan, 323700, Zhejiang, China
4 Longquan Agricultural and Rural Bureau, Longquan, 323700, Zhejiang, China


Medicinal Plant Research, 2024, Vol. 14, No. 6 doi: 10.5376/mpr.2024.14.0027
Received: 08 Oct., 2024 Accepted: 13 Nov., 2024 Published: 28 Nov., 2024
Wu J.F., Wu T., Chen J.R., and Zhang H.J., 2024, Industrial-scale cultivation of Ganoderma lucidum: challenges and technological innovations, Medicinal Plant Research, 14(6): 320-333 (doi: 10.5376/mpr.2024.14.0027)
Ganoderma lucidum is highly valued for its rich bioactive compounds, offering a range of therapeutic effects, including immune enhancement, antioxidant, anti-inflammatory, etc. With the growing global demand for G. lucidum products, industrial-scale cultivation has become increasingly important. This study comprehensively explores the industrial-scale cultivation of G. lucidum, with a focus on analyzing its challenges and corresponding solutions. In response to key issues such as environmental control and contamination management in the cultivation process, innovative methods such as substrate optimization and the introduction of bioreactor technology are proposed to improve the production efficiency, product quality, and sustainability of G. lucidum cultivation. The study demonstrates that industrial-scale cultivation not only reduces costs and increases yield but also ensures the efficacy and quality standards of G. lucidum products. Continued development and promotion of large-scale cultivation techniques are crucial to meeting global market demand, while providing valuable reference and guidance for the application of G. lucidum in pharmaceuticals and health foods.
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